Inhibitory Effect of NS‐398, a Selective Cyclooxygenase‐2 Inhibitor, on Azoxymethane‐induced Aberrant Crypt Foci in Colon Carcinogenesis of F344 Rats

Prostaglandin E(2), which is produced by cyclooxygenase (COX) during arachidonic acid metabolism, is considered to be related to colon Carcinogenesis. Therefore, the effect of NS‐398 (N‐(2‐cyclohexyl‐oxy‐4‐nitrophenyl)methanesulfonamide), a COX‐2 inhibitor, was examined in azoxymethane (AOM)‐induced...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Yoshimi, Naoki, Kawabata, Kunihiro, Hara, Akira, Matsunaga, Kengo, Yamada, Yasuhiro, Mori, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1997
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921322/
https://ncbi.nlm.nih.gov/pubmed/9439679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00328.x
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