Chemopreventive Effect of N‐(2‐Cyclohexyloxy‐4‐nitrophenyl)methane Sulfonamide (NS‐398), a Selective Cyclooxygenase‐2 Inhibitor, in Rat Colon Carcinogenesis Induced by Azoxymethane

Non‐steroidal anti‐inflammatory drugs (NSAIDs) such as sulindac and indomethacin inhibit colon carcinogenesis, and selective cyclooxygenase (COX)‐2 inhibitors are considered to be potential chemopreventive agents without the side effects of usual NSAIDs. We reported that NS‐398, N‐(2‐cyclohexyloxy‐4...

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Pubblicato in:Jpn J Cancer Res
Autori principali: Yoshimi, Naoki, Shimizu, Masahito, Matsunaga, Kengo, Yamada, Yasuhiro, Fujii, Keiko, Hara, Akira, Mori, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1999
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5926081/
https://ncbi.nlm.nih.gov/pubmed/10363578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1999.tb00762.x
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