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Role of Disputed Mutations in the rpoB Gene in Interpretation of Automated Liquid MGIT Culture Results for Rifampin Susceptibility Testing of Mycobacterium tuberculosis

Low-level rifampin resistance associated with specific rpoB mutations (referred as “disputed”) in Mycobacterium tuberculosis is easily missed by some phenotypic methods. To understand the mechanism by which some mutations are systematically missed by MGIT phenotypic testing, we performed an in silic...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Miotto, Paolo, Cabibbe, Andrea M., Borroni, Emanuele, Degano, Massimo, Cirillo, Daniela M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5925711/
https://ncbi.nlm.nih.gov/pubmed/29540456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01599-17
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