Rifampin Resistance Missed in Automated Liquid Culture System for Mycobacterium tuberculosis Isolates with Specific rpoB Mutations

WHO-endorsed phenotypic drug susceptibility testing (DST) methods for Mycobacterium tuberculosis are assumed to be the gold standard for identifying rifampin (RMP) resistance. However, previous results indicated that low-level, yet probably clinically relevant, RMP resistance linked to specific rpoB...

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Bibliographic Details
Main Authors: Rigouts, Leen, Gumusboga, Mourad, de Rijk, Willem Bram, Nduwamahoro, Elie, Uwizeye, Cécile, de Jong, Bouke, Van Deun, Armand
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Mycobacteriology and Aerobic Actinomycetes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719602/
https://ncbi.nlm.nih.gov/pubmed/23761146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02741-12
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