Physical interaction of junctophilin and the Ca(V)1.1 C terminus is crucial for skeletal muscle contraction

Close physical association of Ca(V)1.1 L-type calcium channels (LTCCs) at the sarcolemmal junctional membrane (JM) with ryanodine receptors (RyRs) of the sarcoplasmic reticulum (SR) is crucial for excitation–contraction coupling (ECC) in skeletal muscle. However, the molecular mechanism underlying t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Nakada, Tsutomu, Kashihara, Toshihide, Komatsu, Masatoshi, Kojima, Katsuhiko, Takeshita, Toshikazu, Yamada, Mitsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924888/
https://ncbi.nlm.nih.gov/pubmed/29632175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716649115
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