IMMUNE RESPONSES OF HLA-HIGHLY-SENSITIZED AND NONSENSITIZED PATIENTS TO GENETICALLY-ENGINEERED PIG CELLS

BACKGROUND: We investigated in vitro whether HLA-highly-sensitized patients with end-stage renal disease (ESRD) will be disadvantaged immunologically after a genetically-engineered pig kidney transplant. METHODS: Blood was drawn from patients with a cPRA 99–100% (Gp1, n=10) or cPRA 0% (Gp2, n=12), a...

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Detalhes bibliográficos
Publicado no:Transplantation
Main Authors: Zhang, Zhongqiang, Hara, Hidetaka, Long, Cassandra, Hayato, Iwase, Qi, Haizhi, Macedo, Camilla, Mangiola, Massimo, Zeevi, Adriana, Ezzelarab, Mohamed, Ayares, David, Cooper, David K. C., Wijkstrom, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924598/
https://ncbi.nlm.nih.gov/pubmed/29266033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002060
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