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Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma
Integrins are a large family of adhesion molecules that mediate cell-cell and cell-extracellular matrix interactions. Among the 24 integrin isoforms, many have been found to be associated with tumor angiogenesis, tumor cell migration and proliferation, and metastasis. Integrins, especially αvβ3, αvβ...
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| Pubblicato in: | J Exp Clin Cancer Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5924434/ https://ncbi.nlm.nih.gov/pubmed/29703238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0763-x |
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