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Integrins as therapeutic targets in the organ-specific metastasis of human malignant melanoma

Integrins are a large family of adhesion molecules that mediate cell-cell and cell-extracellular matrix interactions. Among the 24 integrin isoforms, many have been found to be associated with tumor angiogenesis, tumor cell migration and proliferation, and metastasis. Integrins, especially αvβ3, αvβ...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Huang, Ruixia, Rofstad, Einar K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924434/
https://ncbi.nlm.nih.gov/pubmed/29703238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0763-x
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