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MCPIP1 controls allergic airway inflammation by suppressing IL-5-producing Th2 cells through Notch/Gata3 pathway

BACKGROUND: Asthmatic and allergic inflammation is mediated by Th2 cytokines (IL-4, IL-5 and IL-13). Though we have learned much about how Th2 cells are differentiated, the Th2 checkpoint mechanisms remain elusive. OBJECTIVES: In this study, we investigate how monocyte chemotactic protein induced pr...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Peng, Hui, Ning, Huan, Wang, Qinghong, Lu, Wenbao, Chang, Yingzi, Wang, Tony T., Lai, Jinping, Kolattukudy, Pappachan E., Hou, Rong, Hoft, Daniel F., Dykewicz, Mark S., Liu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924426/
https://ncbi.nlm.nih.gov/pubmed/29111212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.09.031
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