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A Subgroup Cluster-Based Bayesian Adaptive Design for Precision Medicine

In precision medicine, a patient is treated with targeted therapies that are predicted to be effective based on the patient’s baseline characteristics such as biomarker profiles. Oftentimes, patient subgroups are unknown and must be learned through inference using observed data. We present SCUBA, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biometrics
Hauptverfasser: Guo, Wentian, Ji, Yuan, Catenacci, Daniel V. T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923898/
https://ncbi.nlm.nih.gov/pubmed/27775814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12613
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