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Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin

To overcome yearly efforts and costs for the production of seasonal influenza vaccines, new approaches for the induction of broadly protective and long-lasting immune responses have been developed in the past decade. To warrant safety and efficacy of the emerging crossreactive vaccine candidates, it...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Hauck, Nastasja C., Kirpach, Josiane, Kiefer, Christina, Farinelle, Sophie, Maucourant, Sophie, Morris, Stephen A., Rosenberg, William, He, Feng Q., Muller, Claude P., Lu, I-Na
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923442/
https://ncbi.nlm.nih.gov/pubmed/29587397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10040148
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