Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer

Background: Although canonical Wnt signaling is known to promote tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), a cancer driven principally by mutant K-Ras, the detailed molecular mechanisms by which the Wnt effector β-catenin regulates such tumorigenesis are largely unknown. We have prev...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Manegold, Philipp, Lai, Keane K. Y., Wu, Yongfeng, Teo, Jia-Ling, Lenz, Heinz-Josef, Genyk, Yuri S., Pandol, Stephen J., Wu, Kaijin, Lin, David P., Chen, Yibu, Nguyen, Cu, Zhao, Yi, Kahn, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923350/
https://ncbi.nlm.nih.gov/pubmed/29596326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10040095
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