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Specific inhibition of CBP/β-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation
Wnt/β-catenin signaling has been shown to promote self-renewal in a variety of tissue stem cells, including neuronal stem cells and hematopoietic stem cells. However, activation of the Wnt/β-catenin pathway promoted and inhibition of the pathway prevented differentiation of neuronal precursor cells....
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1189325/ https://ncbi.nlm.nih.gov/pubmed/16093313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504600102 |
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