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Metabolism, Excretion, and Mass Balance of Solithromycin in Humans

Solithromycin, a novel macrolide and the first fluoroketolide, is being developed as a therapy for community-acquired bacterial pneumonia, with a distinct mechanism that provides activity against macrolide-resistant bacteria. The pharmacokinetics, metabolism, and excretion of solithromycin were stud...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: MacLauchlin, Christopher, Schneider, Stephen E., Keedy, Kara, Fernandes, Prabhavathi, Jamieson, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923163/
https://ncbi.nlm.nih.gov/pubmed/29507061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01474-17
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