Exploring the Pharmacokinetic/Pharmacodynamic Relationship of Relebactam (MK-7655) in Combination with Imipenem in a Hollow-Fiber Infection Model

Resistance to antibiotics among bacterial pathogens is rapidly spreading, and therapeutic options against multidrug-resistant bacteria are limited. There is an urgent need for new drugs, especially those that can circumvent the broad array of resistance pathways that bacteria have evolved. In this s...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Wu, Jin, Racine, Fred, Wismer, Michael K., Young, Katherine, Carr, Donna M., Xiao, Jing C., Katwaru, Ravi, Si, Qian, Harradine, Paul, Motyl, Mary, Bhagunde, Pratik R., Rizk, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5923117/
https://ncbi.nlm.nih.gov/pubmed/29507068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02323-17
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