Population Pharmacokinetic Analysis for Imipenem–Relebactam in Healthy Volunteers and Patients With Bacterial Infections

Relebactam is a small‐molecule β‐lactamase inhibitor developed as a fixed‐dose combination with imipenem/cilastatin. The pharmacokinetics of relebactam and imipenem across 10 clinical studies were analyzed using data from adult healthy volunteers and patients with bacterial infections. Renal functio...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Bhagunde, Pratik, Patel, Parul, Lala, Mallika, Watson, Kenny, Copalu, William, Xu, Ming, Kulkarni, Pooja, Young, Katherine, Rizk, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6813166/
https://ncbi.nlm.nih.gov/pubmed/31508899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12462
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