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Dysfunctional oleoylethanolamide signaling in a mouse model of Prader-Willi syndrome

Prader-Willi syndrome (PWS), the leading genetic cause of obesity, is characterized by a striking hyperphagic behavior that can lead to obesity, type-2 diabetes, cardiovascular disease and death. The molecular mechanism underlying impaired satiety in PWS is unknown. Oleoylethanolamide (OEA) is alipi...

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Détails bibliographiques
Publié dans:Pharmacol Res
Auteurs principaux: Igarashi, Miki, Narayanaswami, Vidya, Kimonis, Virginia, Galassetti, Pietro M., Oveisi, Fariba, Jung, Kwang-Mook, Piomelli, Daniele
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922435/
https://ncbi.nlm.nih.gov/pubmed/28007570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.12.024
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