Preparation, characterization, in vitro and in vivo anti-tumor effect of thalidomide nanoparticles on lung cancer

INTRODUCTION: Thalidomide (THA) is an angiogenesis inhibitor and an efficient inhibitor of the tumor necrosis factor-α (TNF-α). However, the clinical application of THA has been limited due to hydrophobicity of the compound. MATERIALS AND METHODS: To increase the water solubility of THA and in order...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Chen, Long Xia, Ni, Xiao Ling, Zhang, Heng, Wu, Min, Liu, Jing, Xu, Shan, Yang, Ling Lin, Fu, Shao Zhi, Wu, Jingbo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5922239/
https://ncbi.nlm.nih.gov/pubmed/29719394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S159327
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