Preparation, characterization, and in vitro/vivo studies of oleanolic acid-loaded lactoferrin nanoparticles

Oleanolic acid (OA), a pentacyclic triterpene, is used to safely and economically treat hepatopathy. However, OA, a Biopharmaceutics Classification System IV category drug, has low bioavailability owing to low solubility (<1 μg/mL) and biomembrane permeability. We developed a novel OA nanoparticl...

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發表在:Drug Des Devel Ther
Main Authors: Xia, Xiaojing, Liu, Haowei, Lv, Huixia, Zhang, Jing, Zhou, Jianping, Zhao, Zhiying
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2017
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431734/
https://ncbi.nlm.nih.gov/pubmed/28533680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S133997
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