Preparation, characterization, and in vivo pharmacokinetics of nanostructured lipid carriers loaded with oleanolic acid and gentiopicrin

BACKGROUND: The purpose of this work was to develop nanostructured lipid carriers (NLCs) loaded simultaneously with oleanolic acid and gentiopicrin. METHODS: An aqueous dispersion of NLCs was prepared successfully using a film-ultrasonic method, with glycerin monostearate as the solid lipid and olei...

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Detalhes bibliográficos
Main Authors: Zhang, Kunchi, Lv, Shaowa, Li, Xiuyan, Feng, Yufei, Li, Xin, Liu, Lu, Li, Shuang, Li, Yongji
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3758216/
https://ncbi.nlm.nih.gov/pubmed/24009420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S45031
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