Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration

BACKGROUND: Nanostructured lipid carriers (NLCs), composed of solid and liquid lipids, and surfactants are potentially good colloidal drug carriers. Thymoquinone is the main bioactive compound of Nigella sativa. In this study, the preparation, gastroprotective effects, and pharmacokinetic (PK) prope...

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Autori principali: Abdelwahab, Siddig Ibrahim, Sheikh, Bassem Yousef, Taha, Manal Mohamed Elhassan, How, Chee Wun, Abdullah, Rasedee, Yagoub, Umar, El-Sunousi, Rashad, Eid, Eltayeb EM
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3692342/
https://ncbi.nlm.nih.gov/pubmed/23818776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S44108
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