Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo

INTRODUCTION: Nanoparticles (NPs) modified with bio-ligands represent a promising strategy for active targeted drug delivery to tumour. However, many targeted ligands, such as trastuzumab (TMAB), have high molecular weight, limiting their application for targeting. In this study, we prepared Fab’ (a...

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Bibliografske podrobnosti
izdano v:Int J Nanomedicine
Main Authors: Duan, Dongyu, Wang, Aiping, Ni, Ling, Zhang, Liping, Yan, Xiuju, Jiang, Ying, Mu, Hongjie, Wu, Zimei, Sun, Kaoxiang, Li, Youxin
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868600/
https://ncbi.nlm.nih.gov/pubmed/29606874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S153795
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