Intranasal delivery of rotigotine to the brain with lactoferrin-modified PEG-PLGA nanoparticles for Parkinson’s disease treatment

Sustainable and safe delivery of brain-targeted drugs is highly important for successful therapy in Parkinson’s disease (PD). This study was designed to formulate biodegradable poly(ethylene glycol)–poly(lactic-co-glycolic acid) (PEG-PLGA) nanoparticles (NPs), which were surface-modified with lactof...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Bi, Chenchen, Wang, Aiping, Chu, Yongchao, Liu, Sha, Mu, Hongjie, Liu, Wanhui, Wu, Zimei, Sun, Kaoxiang, Li, Youxin
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153272/
https://ncbi.nlm.nih.gov/pubmed/27994458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S120939
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