Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo

INTRODUCTION: Nanoparticles (NPs) modified with bio-ligands represent a promising strategy for active targeted drug delivery to tumour. However, many targeted ligands, such as trastuzumab (TMAB), have high molecular weight, limiting their application for targeting. In this study, we prepared Fab’ (a...

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Bibliografische gegevens
Gepubliceerd in:Int J Nanomedicine
Hoofdauteurs: Duan, Dongyu, Wang, Aiping, Ni, Ling, Zhang, Liping, Yan, Xiuju, Jiang, Ying, Mu, Hongjie, Wu, Zimei, Sun, Kaoxiang, Li, Youxin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2018
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868600/
https://ncbi.nlm.nih.gov/pubmed/29606874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S153795
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