Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo

INTRODUCTION: Nanoparticles (NPs) modified with bio-ligands represent a promising strategy for active targeted drug delivery to tumour. However, many targeted ligands, such as trastuzumab (TMAB), have high molecular weight, limiting their application for targeting. In this study, we prepared Fab’ (a...

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Detaylı Bibliyografya
Yayımlandı:Int J Nanomedicine
Asıl Yazarlar: Duan, Dongyu, Wang, Aiping, Ni, Ling, Zhang, Liping, Yan, Xiuju, Jiang, Ying, Mu, Hongjie, Wu, Zimei, Sun, Kaoxiang, Li, Youxin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2018
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868600/
https://ncbi.nlm.nih.gov/pubmed/29606874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S153795
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