Epigenetic silencing of miR-125b is required for normal B-cell development

Deregulation of several microRNAs (miRs) can influence critical developmental checkpoints during hematopoiesis as well as cell functions, eventually leading to the development of autoimmune disease or cancer. We found that miR-125b is expressed in bone marrow multipotent progenitors and myeloid cell...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Li, Guideng, So, Alex Yick-Lun, Sookram, Reeshelle, Wong, Stephanie, Wang, Jessica K., Ouyang, Yong, He, Peng, Su, Yapeng, Casellas, Rafael, Baltimore, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2018
Schlagworte:
Hematopoiesis and Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921965/
https://ncbi.nlm.nih.gov/pubmed/29555645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-01-824540
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