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Hypermethylation-Associated Silencing of miR-125a and miR-125b: A Potential Marker in Colorectal Cancer

Background. MicroRNAs (miRNAs) have been found to be downregulated in human colorectal cancer (CRC), and some of them may function as tumor suppressor genes (TSGs). Aberrant methylation triggers the inactivation of TSGs during tumorigenesis. Patients and Methods. We investigated the methylation stat...

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Detalhes bibliográficos
Publicado no:Dis Markers
Main Authors: Chen, Hui, Xu, Zhiying
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674596/
https://ncbi.nlm.nih.gov/pubmed/26693202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/345080
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