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CW EPR Parameters Reveal Cytochrome P450 Ligand Binding Modes
Cytochrome P450 monoxygenses (CYPs) utilize heme cofactors to catalyze oxidation reactions. They play a critical role in metabolism of many classes of drugs, are an attractive target for drug development, and mediate several prominent drug interactions. Many substrates and inhibitors alter the spin...
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| Publicado no: | J Inorg Biochem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5921899/ https://ncbi.nlm.nih.gov/pubmed/29530595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2018.02.021 |
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