Significant Correlation of Nitric Oxide Synthase Activity and p53 Gene Mutation in Stage I Lung Adenocarcinoma

Nitric oxide (NO) and its derivatives can directly cause DNA damage and mutation in vitro and may play a role in the multistage carcinogenic process. It has been reported that NO induces mutation in the p53 tumor suppressor gene; we therefore analyzed the relationship between NO synthase 9 activity...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Jpn J Cancer Res
Prif Awduron: Fujimoto, Hisao, Sasaki, Ji‐ichiro, Matsumoto, Mitsuhiro, Suga, Moritaka, Ando, Yukio, Iggo, Richard, Tada, Mitsuhiro, Saya, Hideyuki, Ando, Masayuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 1998
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921893/
https://ncbi.nlm.nih.gov/pubmed/9738975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb03273.x
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