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Nitric Oxide Generation from Hydroxyurea via Copper‐catalyzed Peroxidation and Implications for Pharmacological Actions of Hydroxyurea
We investigated the generation of nitric oxide (NO) by H(2)O(2)dependent peroxidation of hydroxyurea in the presence of copper‐containing proteins such as Cu, Zn‐snperoxide dismutase (Cu, Zn‐SOD) or ceruloplasmin as a catalyst. In the reaction mixture of hydroxyurea, Cu, Zn‐SOD, and H(2)O(2), “NO ge...
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| Gepubliceerd in: | Jpn J Cancer Res |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Blackwell Publishing Ltd
1997
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5921347/ https://ncbi.nlm.nih.gov/pubmed/9473738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00349.x |
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