Inhibitory Effects of Nabumetone, a Cyclooxygenase‐2 Inhibitor, and Esculetin, a Lipoxygenase Inhibitor, on N‐Methyl‐N‐nitrosourea‐induced Mammary Carcinogenesis in Rats

We investigated the modifying effects of nabumetone, a relatively selective cyclooxygenase‐2 inhibitor, and esculetin, a lipoxygenase inhibitor, on N‐methyl‐N‐nitrosourea(MNU)‐induced mammary carcinogenesis in female Sprague‐Dawley rats. A total of 124 rats, 6 weeks old, were divided into 6 groups....

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Matsunaga, Kengo, Yoshimi, Naoki, Yamada, Yasuhiro, Shimizu, Masahito, Kawabata, Kunihiro, Ozawa, Yuki, Hara, Akira, Mori, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921855/
https://ncbi.nlm.nih.gov/pubmed/9685852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb03289.x
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