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Novel Point Mutations and Allele Loss at the RET Locus in Sporadic Medullary Thyroid Carcinomas

Germline mutations in the RET proto‐oncogene have been shown to be the underlying cause of multiple endocrine neoplasia type 2 (MEN 2A and 2B) and familial medullary thyroid carcinoma (FMTC). Some cases of sporadic medullary thyroid carcinoma (sporadic MTC) are reported to have specific codon 918, 8...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Uchino, Shinya, Noguchi, Shiro, Adachi, Mitsuo, Sato, Mari, Yamashita, Hiroyuki, Watanabe, Shin, Murakami, Tsukasa, Toda, Masakatsu, Murakami, Nobuo, Yamashita, Hiroto
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921821/
https://ncbi.nlm.nih.gov/pubmed/9617347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1998.tb00579.x
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