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C3G dynamically associates with nuclear speckles and regulates mRNA splicing

C3G (Crk SH3 domain binding guanine nucleotide releasing factor) (Rap guanine nucleotide exchange factor 1), essential for mammalian embryonic development, is ubiquitously expressed and undergoes regulated nucleocytoplasmic exchange. Here we show that C3G localizes to SC35-positive nuclear speckles...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Shakyawar, Dhruv Kumar, Muralikrishna, Bhattiprolu, Radha, Vegesna
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921577/
https://ncbi.nlm.nih.gov/pubmed/29496966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0442
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