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C3G dynamically associates with nuclear speckles and regulates mRNA splicing

C3G (Crk SH3 domain binding guanine nucleotide releasing factor) (Rap guanine nucleotide exchange factor 1), essential for mammalian embryonic development, is ubiquitously expressed and undergoes regulated nucleocytoplasmic exchange. Here we show that C3G localizes to SC35-positive nuclear speckles...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Shakyawar, Dhruv Kumar, Muralikrishna, Bhattiprolu, Radha, Vegesna
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921577/
https://ncbi.nlm.nih.gov/pubmed/29496966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0442
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