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A role for TREX components in the release of spliced mRNA from nuclear speckle domains
The TREX complex, which functions in mRNA export, is recruited to mRNA during splicing. Both the splicing machinery and the TREX complex are concentrated in 20–50 discrete foci known as nuclear speckle domains. Using a model system where CMV-DNA constructs were microinjected into HeLa cell nuclei, w...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3793428/ https://ncbi.nlm.nih.gov/pubmed/20981025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1103 |
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