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Effect of Glutathione Depletion on Cisplatin Resistance in Cancer Cells Transfected with the γ‐Glutamylcysteine Synthetase Gene

Overexpression of the human γ‐glutamylcysteine synthetase (γ‐GCS) gene resulted in cisplatin resistance with an increased glutathione (GSH) content, increased ATP‐dependent glutatbione S‐conjugate export pump (GS‐X pump) activity and decreased platinum accumulation in human lung cancer cells transfe...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Jpn J Cancer Res
Päätekijät: Kurokawa, Hirokazu, Nishio, Kazuto, Ishida, Tomoyuki, Arioka, Hitoshi, Fukuoka, Kazuya, Nomoto, Taisuke, Fukumoto, Hisao, Yokote, Hideyuki, Saijo, Nagahiro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Publishing Ltd 1997
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921367/
https://ncbi.nlm.nih.gov/pubmed/9119737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1997.tb00354.x
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