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Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells

In utero exposure to certain phthalate esters results in testicular toxicity, characterized at the tissue level by induction of multinucleated germ cells (MNGs) in rat, mouse, and human fetal testis. Phthalate exposures also result in a decrease in testicular testosterone in rats. The anti-androgeni...

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Dades bibliogràfiques
Publicat a:Toxicol Lett
Autors principals: Spade, Daniel J., Bai, Cathy Yue, Lambright, Christy, Conley, Justin M., Boekelheide, Kim, Gray, L. Earl
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921076/
https://ncbi.nlm.nih.gov/pubmed/29571896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2018.03.018
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