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Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells

In utero exposure to certain phthalate esters results in testicular toxicity, characterized at the tissue level by induction of multinucleated germ cells (MNGs) in rat, mouse, and human fetal testis. Phthalate exposures also result in a decrease in testicular testosterone in rats. The anti-androgeni...

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Detalles Bibliográficos
Publicado en:Toxicol Lett
Main Authors: Spade, Daniel J., Bai, Cathy Yue, Lambright, Christy, Conley, Justin M., Boekelheide, Kim, Gray, L. Earl
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5921076/
https://ncbi.nlm.nih.gov/pubmed/29571896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2018.03.018
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