Formation and Removal of DNA Adducts in the Liver of Rats Chronically Fed the Food‐borne Carcinogen, 2‐Amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline

Effects of chronic administration of 2‐amino‐3,8‐dimethylimidazo[4,5‐f]quinoxaline (MeIQx) at 0.4, 8 and 400 ppm in the diet on DNA adduct formation and removal in the rat liver were examined by the (32)P‐postlabeling method. The 0.4 and 8 ppm doses for 40 weeks resulted in time‐dependent increases...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Hirose, Misako, Wakabayashi, Keiji, Ochiai, Masako, Kushida, Hiromi, Sato, Hidetaka, Sugimura, Takashi, Nagao, Minako
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1995
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920865/
https://ncbi.nlm.nih.gov/pubmed/7622414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb02428.x
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