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Estimation of cis-eQTL Effect Sizes Using a Log of Linear Model

The study of expression Quantitative Trait Loci (eQTL) is an important problem in genomics and biomedicine. While detection (testing) of eQTL associations has been widely studied, less work has been devoted to the estimation of eQTL effect size. To reduce false positives, detection methods frequentl...

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Detalhes bibliográficos
Publicado no:Biometrics
Main Authors: Palowitch, John, Shabalin, Andrey, Zhou, Yi-Hui, Nobel, Andrew B., Wright, Fred A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920774/
https://ncbi.nlm.nih.gov/pubmed/29073327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12810
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