XIAP impairs mitochondrial function during apoptosis by regulating the Bcl-2 family in renal cell carcinoma

Efficient apoptosis requires Bcl-2 family-mediated mitochondrial outer membrane permeabilization (MOMP), which releases pro-apoptotic proteins to the cytosol, activating apoptosis and inhibiting X-linked inhibitor of apoptosis protein (XIAP). XIAP is a member of the inhibitors of apoptosis protein f...

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Dades bibliogràfiques
Publicat a:Exp Ther Med
Autors principals: Chen, Chao, Liu, Tian Shu, Zhao, Si Cong, Yang, Wen Zheng, Chen, Zong Ping, Yan, Yong
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2018
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920643/
https://ncbi.nlm.nih.gov/pubmed/29731840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.5974
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