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XIAP impairs mitochondrial function during apoptosis by regulating the Bcl-2 family in renal cell carcinoma
Efficient apoptosis requires Bcl-2 family-mediated mitochondrial outer membrane permeabilization (MOMP), which releases pro-apoptotic proteins to the cytosol, activating apoptosis and inhibiting X-linked inhibitor of apoptosis protein (XIAP). XIAP is a member of the inhibitors of apoptosis protein f...
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| Publicado no: | Exp Ther Med |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5920643/ https://ncbi.nlm.nih.gov/pubmed/29731840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.5974 |
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