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Induction of Erythroid Differentiation by 5‐Fluorouracil in K562 Leukemia Cells

K562 cell line, established from a patient in the blast crisis of chronic myeloid leukemia, expresses high levels of c‐myc and bcr/abl gene products. Exposure of K562 cells to 5‐fluorouracil (5‐FU) resulted in a marked benzidine‐positive erythroid differentiation with concomitant reduction in cell p...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Yang, Ya‐Wun, Chang, and Yea‐Hueay
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920591/
https://ncbi.nlm.nih.gov/pubmed/7493914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb03006.x
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