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Inhibition of abl Oncogene Tyrosine Kinase Induces Erythroid Differentiation of Human Myelogenous Leukemia K562 Cells

The human chronic myelogenous leukemia cell line K562 expresses a structurally altered c‐abl protein with tyrosine kinase activity. Erythroid differentiation of K562 cells was induced by tyrosine kinase inhibitors, but not by other kinase inhibitors. Treatment of K562 cells with 5'd(TACTGGCCGCT...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Honma, Yoshio, Okabe‐Kado, Junko, Kasukabe, Takashi, Hozumi, Motoo, Umezawa, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917994/
https://ncbi.nlm.nih.gov/pubmed/2125038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02524.x
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