Inhibition of abl Oncogene Tyrosine Kinase Induces Erythroid Differentiation of Human Myelogenous Leukemia K562 Cells

The human chronic myelogenous leukemia cell line K562 expresses a structurally altered c‐abl protein with tyrosine kinase activity. Erythroid differentiation of K562 cells was induced by tyrosine kinase inhibitors, but not by other kinase inhibitors. Treatment of K562 cells with 5'd(TACTGGCCGCT...

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Xehetasun bibliografikoak
Argitaratua izan da:Jpn J Cancer Res
Egile Nagusiak: Honma, Yoshio, Okabe‐Kado, Junko, Kasukabe, Takashi, Hozumi, Motoo, Umezawa, Kazuo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Publishing Ltd 1990
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917994/
https://ncbi.nlm.nih.gov/pubmed/2125038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02524.x
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