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Inhibition of abl Oncogene Tyrosine Kinase Induces Erythroid Differentiation of Human Myelogenous Leukemia K562 Cells

The human chronic myelogenous leukemia cell line K562 expresses a structurally altered c‐abl protein with tyrosine kinase activity. Erythroid differentiation of K562 cells was induced by tyrosine kinase inhibitors, but not by other kinase inhibitors. Treatment of K562 cells with 5'd(TACTGGCCGCT...

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Dettagli Bibliografici
Pubblicato in:Jpn J Cancer Res
Autori principali: Honma, Yoshio, Okabe‐Kado, Junko, Kasukabe, Takashi, Hozumi, Motoo, Umezawa, Kazuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5917994/
https://ncbi.nlm.nih.gov/pubmed/2125038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1990.tb02524.x
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