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Rap1 in endothelial biology
PURPOSE OF REVIEW: Ubiquitously-expressed small GTPase Rap1 is a key modulator of integrin- and cadherin-regulated processes. In endothelium Rap1 promotes angiogenesis and endothelial barrier (EB) function, acting downstream from cAMP-activated Rap1GEF, Epac. Recent in vivo studies in mouse models h...
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| 出版年: | Curr Opin Hematol |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5920548/ https://ncbi.nlm.nih.gov/pubmed/28178039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000332 |
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