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MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options?

Human hepatocellular carcinoma (HCC) is the fifth most common cancer and is associated with poor prognosis worldwide. The molecular mechanisms underlying the pathogenesis of HCC have been an area of continuing interest, and recent studies using next generation sequencing (NGS) have revealed much reg...

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Библиографические подробности
Опубликовано в: :J Clin Med
Главный автор: Azer, Samy A.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920438/
https://ncbi.nlm.nih.gov/pubmed/29584707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm7040064
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