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MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options?

Human hepatocellular carcinoma (HCC) is the fifth most common cancer and is associated with poor prognosis worldwide. The molecular mechanisms underlying the pathogenesis of HCC have been an area of continuing interest, and recent studies using next generation sequencing (NGS) have revealed much reg...

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Detalhes bibliográficos
Publicado no:J Clin Med
Autor principal: Azer, Samy A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920438/
https://ncbi.nlm.nih.gov/pubmed/29584707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm7040064
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