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MDM2-p53 Interactions in Human Hepatocellular Carcinoma: What Is the Role of Nutlins and New Therapeutic Options?

Human hepatocellular carcinoma (HCC) is the fifth most common cancer and is associated with poor prognosis worldwide. The molecular mechanisms underlying the pathogenesis of HCC have been an area of continuing interest, and recent studies using next generation sequencing (NGS) have revealed much reg...

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Vydáno v:J Clin Med
Hlavní autor: Azer, Samy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920438/
https://ncbi.nlm.nih.gov/pubmed/29584707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm7040064
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