Blocking fatty acid–fueled mROS production within macrophages alleviates acute gouty inflammation

Gout is the most common inflammatory arthritis affecting men. Acute gouty inflammation is triggered by monosodium urate (MSU) crystal deposition in and around joints that activates macrophages into a proinflammatory state, resulting in neutrophil recruitment. A complete understanding of how MSU crys...

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Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Hall, Christopher J., Sanderson, Leslie E., Lawrence, Lisa M., Pool, Bregina, van der Kroef, Maarten, Ashimbayeva, Elina, Britto, Denver, Harper, Jacquie L., Lieschke, Graham J., Astin, Jonathan W., Crosier, Kathryn E., Dalbeth, Nicola, Crosier, Philip S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919807/
https://ncbi.nlm.nih.gov/pubmed/29584621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94584
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