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Blocking fatty acid–fueled mROS production within macrophages alleviates acute gouty inflammation
Gout is the most common inflammatory arthritis affecting men. Acute gouty inflammation is triggered by monosodium urate (MSU) crystal deposition in and around joints that activates macrophages into a proinflammatory state, resulting in neutrophil recruitment. A complete understanding of how MSU crys...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5919807/ https://ncbi.nlm.nih.gov/pubmed/29584621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94584 |
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