Blocking fatty acid–fueled mROS production within macrophages alleviates acute gouty inflammation

Gout is the most common inflammatory arthritis affecting men. Acute gouty inflammation is triggered by monosodium urate (MSU) crystal deposition in and around joints that activates macrophages into a proinflammatory state, resulting in neutrophil recruitment. A complete understanding of how MSU crys...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Hall, Christopher J., Sanderson, Leslie E., Lawrence, Lisa M., Pool, Bregina, van der Kroef, Maarten, Ashimbayeva, Elina, Britto, Denver, Harper, Jacquie L., Lieschke, Graham J., Astin, Jonathan W., Crosier, Kathryn E., Dalbeth, Nicola, Crosier, Philip S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919807/
https://ncbi.nlm.nih.gov/pubmed/29584621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94584
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