Development and Characterization of Chimeric Anti‐carcinoembryonic Antigen Monoclonal Antibodies and Their Fab Fragments

In an attempt to reduce the immunogenicity of two different murine anti‐carcinoembryonic antigen (CEA) monoclonal antibodies (MAbs), KM10 and A10, we produced recombinant mouse/human chimeric MAbs and the respective Fab fragments carrying the variable regions of the murine MAbs. Chimeric A10 Fab fra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Jpn J Cancer Res
Egile Nagusiak: Kamigaki, Takashi, Ohyanagi, Harumasa, Yamamoto, Masahiro, Kaneda, Teruo, Goto, Takashi, Ohmura, Takao, Yokoyama, Kazumasa, Saitoh, Yoichi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Publishing Ltd 1994
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919441/
https://ncbi.nlm.nih.gov/pubmed/8188529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02097.x
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